Original Research ArticleInternational Journal of Advances in Medicine
Publication: Role of serum interleukin-6 in heart failure
Int J Adv Med. 2018;5(4):936-940.DOI10.18203/2349-3933.ijam20183123
Abstract
Background A growing body of evidence suggests that inflammation plays the key role in different cardiovascular diseases. But very study has been done so far in relation to serum interleukin-6 in heart failure patients. The aim of the study was to measure serum interleukin-6 in heart failure patients.
Methods Total 22 heart failure patients and 22 age and sex matched controls were included in this study from August 2015 to June 2016 for serum analysis of interleukin-6.
Results serum interleukin-6 was significantly [median(IQR) 14.3(26.2) pg/mL] increased in heart failure patients compared to age and sex matched controls [median(IQR) 0(2.4) pg/mL].
Conclusions Even though little is known about function of interleukin-6 in heart failure patients, this study shows that increased level of IL-6 in heart failure patients plays an important role as a pro-inflammatory marker in development of cardiovascular disease i.e. heart failure.
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Affiliations
- Department of Biochemistry, HBTMC and RNCH, Mumbai, Maharashtra, India
- Department of Biochemistry, Seth G.S. Medical College and KEM Hospital, Mumbai, Maharashtra, India
- Department of Obstetrics and Gyanaecology, HBTMC and RNCH, Mumbai, Maharashtra, India
- Department of Cardiology, Dr. Milind Phadakes Cardiac Center, Mumbai, Maharashtra, India