Publication:

Human immunodeficiency virus infected patient with cerebral infarction without non-infectious comorbidities

Human immunodeficiency virus (HIV) has been proven to increase the risk of stroke. The annual incidence rate of ischemic stroke in HIV was 216 per 100,000. Multiple factors, linked to HIV infection, could increase the susceptibility of developing cerebrovascular diseases (CVD), such as opportunistic infections, coagulation abnormalities, dyslipidemia, and toxicity of antiretroviral therapy (ART). HIV is thought to contribute to the incidence of stroke through both HIV-associated and traditional stroke risk factors. ARTs, namely protease inhibitors and nucleoside reverse transcriptase inhibitors, can increase the incidence of stroke.