Publication:

Clinical analysis of vulvar cancer

Background The purpose of this study is to understand the incidence, related factors, and the prognosis factors in order to avoid risk, proper method of diagnosis and treatment and reduce complications and provide the basis.

Methods 85 Vulvar cancer (VC) patients treated in our hospital from 2002.10 to 2012.10 were collected and analyzed by retrospective comparative methods. SPSS19.0 application software was used for the statistical analysis. The clinical data are analyzed by chi-square and F test statistic methods. P < 0.05 was a significant difference between the judgment standard.

Results During 10 years, we treated 3391 cases of the primary malignant tumors including 85 VC cases; VC was 2.89% (85/3391). The age was between 24～88 years old, mean was 57.09±12.93 yrs. old, variable age of the VC had been juvenescence trend (F=6. 013，P=0.016＜0.05＝). The differences between the urban and rural residential area have some influence to the onset of VC. Rural patients are more than urban patients. By statistical analysis, region distribution in these two groups was remarkably different=4.16，P=0.045＜0.05, but the urban proportion of patients in different years has no difference（χ2=0.080, P=0.777）.

Conclusion The number of cases increased progressively in young age. VC patients were more in rural area than urban. History of malignant tumor and obesity has the positive correlation with VC. High-risk groups should be alert to the possibility of VC. Preoperative diagnosis should be Colposcopic, biopsy in order to improve the accuracy of earlier diagnosis. Vulvar resects have an effect on the healing of the incision. Follow-up rate is low; It is difficult to say statistically survival rate is 5 years.