Publication:

A study on associations and influence of health determinants on systolic and diastolic blood pressure

Background The aim of the study was to assess the prevalence of hypertension among Indian urban educated population and evaluate the association of various modifiable and non-modifiable risk factors on the development of systolic blood pressure (SBP) and diastolic blood pressure (DBP).

Methods The retrospective study comprised of medical data obtained from 175 individuals who had undergone routine annual medical check-up during the period 2016 -2017. The data was analysed and interpreted using summary statistics, correlations and linear regression analysis. Most of the variables were measured values.

Results Out of 175 reports analysed, 40 (22.9%) individuals comprising of 29 males and 11 females were found to be hypertensives. Isolated systolic hypertension was present in 4 (2.3%) individuals, isolated diastolic hypertension in 26 (14.9%) individuals and in 10 (5.7%) individuals both systolic and diastolic blood pressure was raised. Significant correlations were observed. Multiple linear regression showed significant positive influence of DBP, age and BMI on SBP whereas serum vitamin D level and left ventricular cardiac ejection fraction was negatively influencing SBP (R²=0.638, p=0.000). furthermore, multiple regression analysis with DBP as the dependent variable showed SBP, and serum vitamin D level to be the significant influencing determinants (R²=0.602, p=0.000).

Conclusions The present study on the Influence of modifiable and non-modifiable risk factors on development of SBP and DBP improves knowledge for better preventive strategies.