Original Research ArticleInternational Journal of Basic & Clinical Pharmacology
Publication: Comparative study of 0.5% ropivacaine and 0.5% bupivacaine for brachial plexus block by supraclavicular approach for upper limb surgeries
Int J Basic Clin Pharmacol. 2016;5(4):1205-1209.DOI10.18203/2319-2003.ijbcp20162243
Abstract
Background Present study was undertaken to evaluate the clinical efficacy of 0.5% ropivacaine for supraclavicular bronchial plexus block for upper limb surgeries and comparing it with 0.5% bupivacaine in terms of characteristics of supraclavicular blockade and side effects.
Methods The design was a prospective double blind randomized study enrolling 60 patients of either sex, ASA I and II, were randomly allocated into two groups in which supraclavicular brachial plexus block was performed with nerve stimulator using 30 ml of ropivacaine 0.5% and bupivacaine 0.5% respectively. The onset and duration of sensory and motor block and possible adverse events were recorded.
Results Ropivacaine had earlier onset of sensory and motor blockade compared to bupivacaine. The duration of sensory and motor blockade was longer in group of patients treated with ropivacaine than in bupivacaine group. No statistically significant difference was found in quality of blocks in both groups. There were no adverse effects observed in the study.
Conclusions Ropivacaine 0.5% can be safely used as an alternative to bupivacaine 0.5% in supraclavicular bronchial plexus block.
Keywords
Affiliations
- Department of Anaesthesiology, Lokmanya Tilak Municipal Medical and General Hospital, Sion, Mumbai, India
