Publication:

A rare case of Crigler-Najjar syndrome type II with pregnancy

Crigler-Najjar syndrome (CNS) has been rarely described during pregnancy with only few case reports available in literature, CNS is expressed in two forms, CNS type I and CNS type II; Type I CNS results in severe unconjugated hyperbilirubinemia and neurological impairment in newborn and is fatal. Type II CNS results in milder unconjugated hyperbilirubinemia responding to Phenobarbital treatment with better outcome.