Publication:

How much antibiotic for cesarean section and hysterectomy: short course versus long course

Background Objective of current study was to compare cost and efficacy of short course and long course prophylactic antibiotics for hysterectomy and cesarean section.

Methods The current study is observational study. It has two antibiotic regimens a short course and a long course and these are compared for average duration of antibiotics, average cost of antibiotics, and outcome measures such as wound infection and febrile illness. Data were analyzed using t test, Chi-squared test, Epi info software used for analysis.

Results The short course low cost regimen is as effective as more expensive long course regimen, with no significant difference of wound infections and febrile morbidity (P >0.05).

Conclusions No statistical difference as regard wound infection and febrile morbidity in short course and long course of prophylactic antibiotic therapy in cesarean section and hysterectomy. There is statistical difference in antibiotic cost between two regimen, short course and long course for cesarean section and hysterectomy. The cost of antibiotic is 5.53 times less in short course regimen for cesarean section and hysterectomy when compared with long course regimen.