Publication:

Clinical profile in metabolic syndrome

Background The metabolic syndrome is a condition characterized by a constellation of metabolic disorders including: abdominal obesity, insulin resistance/glucose intolerance, atherogenic dyslipidemia [elevated Triglyceride (TG), and lower High Density Lipoprotein (HDL-c)], raised blood pressure, proinflammatory and prothrombotic state. It was referred to as the “X syndrome” by Kylin in the 1920’s and described as a phenomenon of the clustering of obesity, hypertension, and gout.1 Aims and objects: To correlate different clinical and biochemical parameters in metabolic syndrome among the staff of   Hospital in Imphal.

Methods A total of 239 staffs were selected randomly from the Hospital, Imphal, Manipur. Sample size was calculated based on the prevalence of metabolic syndrome of 33.2%4 with 95% precision, coming to a sample size of 237.

Results Metabolic syndrome was found in 49 out of 239 staffs and its prevalence was 21% which increased with age. There was a strong association between metabolic syndrome and obesity. There is lower prevalence rate of metabolic syndrome among the staff compared to other studies. This may have resulted from a number of factors including younger age, physical activities and ethnic origin.

Conclusions Measuring MetS components is necessary for the early detection of this abnormal condition and early intervention.