Publication:

Efficacy of colposcopy technique with Pap smear and histology in screening of cervical lesions

Background In India the most common genital cancer among women is carcinoma of the cervix (80%). The objective of the study is analysis of efficacy of colposcopy technique with Pap smear and histology in screening of cervical lesions.

Methods Patients above 18 years of age with varied parity and socioeconomic status attending out-patient clinics were studied for correlation between cytology, colposcopy and colposcopically directed biopsy for a one year period.

Results In cytology and colposcopic directed biopsy sensitivity is 81%, specificity is 95%, false positive is 4.9%, false negative is 18% and accuracy is 92%. In colposcopy and directed biopsy sensitivity is 94%, specificity is 91%, false positive is 7.4%, false negative is 5.8% and accuracy is 92.85%. Colposcopy helps to reduce false negative cases seen in cytology.

Conclusions In our study overall incidence of CIN was 19, among them CIN1 in 9%, CIN2 in 4%, CIN3 in 4% and malignancy in 2% cases. Higher sensitivity in colposcopy and directed biopsy 94%, higher specificity 95% in cytology as compared to colposcopy. This emphasizes the use of all 3 methods Papincolaou cytology, colposcopy and histology is complementary to each other and helps to reduce false negative cases.