Publication:

Exacerbation of vitiligo following oral tranexamic acid therapy administered for the treatment of melasma: a case report

The presence of vitiligo has been identified as an independent risk factor for the development of melasma, and the two conditions may coexist in clinical practice. However, evidence regarding the optimal management of melasma in patients with concomitant vitiligo remains limited. Oral tranexamic acid has been increasingly recognized in recent years as a safe and effective treatment option for melasma. Nonetheless, its safety profile in patients who also have vitiligo has not been clearly established. In this report, we describe a case of a patient with melasma and coexisting vitiligo who developed a vitiligo flare following oral tranexamic acid therapy.