Publication:

Adult onset Still’s disease: a diagnostic challenge

Adult Still’s disease (ASD) is a systemic inflammatory disorder of unknown etiology, typically characterized by a clinical triad of daily spiking high fevers, evanescent rash, and arthritis. This report described a 26-year-old male who presented with these symptoms along with raised liver enzymes and hyperferritinemia. After ruling out systemic infections, localized infections, malignancies and other rheumatological diseases, Adult onset Still’s disease diagnosis was made according to Yamaguchi criteria (having 4 major features and 3 minor features). AOSD is a heterogeneous and rare disease and the lack of serologic markers as a true gold standard makes diagnosis difficult.