Original Research ArticleInternational Journal of Research in Dermatology

Publication:
Efficacy and tolerability of Arnophyte cream for herpes infection, in subjects with early signs and symptoms of recurrent HSV-2

Int J Res Dermatol. 2019;5(4):792-799.DOI10.18203/issn.2455-4529.IntJResDermatol20194670

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Abstract

Background Arnophyte® cream developed from Ficus arnottiana plant extract showed strong potential as an Anti-viral agent. The objective of the study was to evaluate the efficacy and tolerability of Arnophyte® cream in subjects with early signs and symptoms of recurrent HSV-2.

Methods The treatment was given for a period of 14 days. The study outcomes measured were assessment of reduction in pain using the visual analogue score (VAS), the changes in the quality of life index for recurrent genital herpes (GHQoLr); physician’s and patient’s global assessment of the therapy, signs and symptoms associated with HSV-2 and healing of the target lesion on baseline, day 2, day 4, day 7 and day 15.

Results Arnophyte® cream showed significant reduction in the signs and symptoms of herpes infection. The cream was well tolerated with no serious adverse events observed.

Conclusions Arnophyte® cream can be considered as a possible therapeutic option for the treatment of recurrent herpes infections in both HSV-1 and HSV-2.

Keywords

Affiliations

  1. Department of Phytomedicines, Piramal Enterprises Limited, Mumbai, Maharashtra, India
  2. Sai Medi Centre, Mumbai, Maharashtra, India
  3. Life Veda Treatment and Research Centre, Mumbai, Maharashtra, India

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