Publication:

Evaluation of vitamin D status, selenium and C-reactive protein level in psoriasis

Background Psoriasis is an inflammatory skin disease associated with a variety of clinical conditions. Study aim to evaluate the association of vitamin D, selenium and C-reactive protein (CRP) levels in psoriasis.

Methods This hospital-based case-control study involved 50 psoriasis cases and 47 healthy individuals. Serum vitamin D, selenium and CRP levels were measured, and the general demographic values were also recorded.

Results Statistical analysis revealed that vitamin D levels are significantly lower in psoriasis (p<0.005). Among the demographic parameters, obesity was found more common among psoriasis cases than controls. Serum selenium and CRP levels were not significantly different between the two groups.

Conclusions Vitamin D deficiency is strongly associated with psoriasis. Vitamin D supplementation can be useful in psoriasis management and also in the reduction of obesity. Serum selenium and CRP levels aren’t significant markers to demonstrate psoriasis.