Publication:

A prospective study to assess role of serum lactate dehydrogenase in prediction of adverse outcomes of pre-eclampsia and eclampsia

Background Pregnancy induced hypertension is one of the most dreaded complication in developing countries. The purpose of this study is to evaluate incidence, risk factors and complications of pre-eclampsia and eclampsia and its relation to serum LDH levels. This was done with a view to making recommendations towards furtherance of objectives of this initiative.

Methods 380 patients with diagnosed eclampsia and preeclampsia were included based on a proforma.

Results Higher grades of proteinuria, higher BP and serum LDH levels >600 IU/L are significantly associated with adverse maternal and fetal outcome.

Conclusions LDH co-relates with adversity of maternal and fetal outcome in eclampsia and pre-eclampsia.